CYP2D6*2_p.S486T Reference Standard

CBPA0002

询价

索取COA

产品描述

产品数据库

Introduction
Format	Genomic DNA
Description	CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients.

Technical Data
Gene	CYP2D6
AA Change	p.S486T
DNA Change	NM_000106.6:c.1457G>C
Chr position (GRCh38)	chr22:42126611
Allelic Frequency	50%
Zygosity	Heterozygous

Product Information
Intended Use	Research Use Only
Unit Size	1ug
Concentration	Download for COA
Purofication	Download for COA
DNA electrophoresis	Download for COA
Sanger sequencing
Storage	2-8°C
Expiry	36 months from the date of manufacture

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