CYP2D6*10 Reference Standard

CBPA0072

询价

索取COA

产品描述

产品数据库

Introduction
Format	Genomic DNA
Description	CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients.

Technical Data
Gene	CYP2D6
Mutation Type 1	AA Change: p.S486T
	DNA Change: NM_000106.6:c.1457G>C
	Chr position (GRCh38): chr22:42126611
Mutation Type 2	AA Change: p.P34S
	DNA Change: NM_000106.6:c.100C>T
	Chr position (GRCh38): chr22:42130692
Mutation Type 3	AA Change: N/A
	DNA Change: NM_000106.6:c.408G>C
	Chr position (GRCh38): chr22:42129130
Allelic Frequency	100%
Zygosity	Homozygous

Product Information
Intended Use	Research Use Only
Unit Size	1ug
Concentration	Download for COA
Purofication	Download for COA
DNA electrophoresis	Download for COA
Sanger sequencing	Figure 1. CYP2D610 Reference Standard p.S486T Figure 2. CYP2D610 Reference Standard p.P34S Figure 3. CYP2D6*10 Reference Standard c.408G>C
Storage	2-8°C
Expiry	36 months from the date of manufacture

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• CYP2D6*10 Reference Standard • CYP2D6*2 Reference Standard • CYP2D6*2_p.R296C Reference Standard • CYP2D6*2_p.S486T Reference Standard • CYP2D6*2_p.S486T Reference Standard • CYP2D6*4 Reference Standard • CYP2D6*4 Reference Standard • CYP2D6*41 Reference Standard

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