FCGR2B/HEK293
CBP74078
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| I. Background | |
| The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. | |
| II. Description | |
| Recombinant HEK293 cells constitutively expressing human FCGR2B. | |
| III. Introduction | |
| Host Cell: | HEK293 |
| Expressed gene: | FCGR2B（FcγRIIb） |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | CD32B, FCG2, Fc gamma receptor, Fcgamma receptor |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+100μg/ml Hygromycin B |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Description of Host Cell Line | |
| Organism: | Human |
| Tissue: | kidney |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| Ⅴ. Representative Data | |
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Figure 1.Recombinant HEK293 cells constitutively expressing FCGR2B(FcγRIIb). |
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