OCI-M2（人急性粒细胞白血病）
CBP61206
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| I. General information | |
| Synonyms: | OCI-M2 |
| Background: | established in 1984 from the leukemic cells of a 56-year-old patient with erythroleukemia (AML-M6), representing the end stage of a previously identified myelodysplastic syndrome; described in the literature to differentiate along the erythroid or megakaryocytic/monocytic lineage after stimulation with erythroid inducers or phorbol esters, respectively; described in the literature to constitutively and inducibly secrete platelet-derived growth factor (PDGF)-like proteins; contamination with Mycobacterium was eliminated with Kanamycin |
| Species: | human (Homo sapiens) |
| Tissue: | N/A |
| Disease: | acute myelocytic leukemia |
| Gender: | N/A |
| Morphology: | round cells growing singly or in clusters in suspension, occasionally a few cells become adherent; |
| Growth Mode: | N/A |
| Doubling Time: | ca. 36 hours |
| DNA Profile: | N/A Our Cell Line Authentication Service |
| Culture Medium: |
IMDM+20%FBS OCI-M2完全培养基，# CBP61206M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Mycoplasma: | negative in microbiological culture, PCR assays |
| Immunology: | CD3 -, CD13 +, CD14 -, CD19 -, CD33 +, CD71 +, CD235a +; |
| Fingerprint: | fluorescent nonaplex PCR of short tandem repeat markers revealed a unique DNA profile |
| Species: | confirmed as human by cytogenetics |
| Cytogenetics: | human hyperdiploid karyotype with 4% polyploidy; 51(46-51)<2n>XX, +6, +8, +20, -21, +3mar, der(X)t(X;8)(q23;q23), add(9)(p23)del(9)(p12p21), t(10;12)(p12;p12), del(17)(q11q21.1); no reference karyotype available |
| Virus | PCR: EBV -, HBV -, HCV -, HIV-1 -, HIV-2 -, HTLV-I/II -, MLV -, SMRV - |
| Comments: | For more information, please contact us (4008-750-250). |
